A Disapproved Keyword Issue means the ad platform has rejected one of your live keywords under its advertising policies, so it can't trigger your ads. It covers Google Ads and Microsoft Ads.
Fix it
Open the Issue. It shows the keyword, the reason it was disapproved, and its campaign and ad group.
In the ad platform, change the keyword or remove it.
Back in Opteo, click Recheck, for example Recheck Google Ads.